Over-the-Counter Nasal Spray Could Be Effective Against COVID-19

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Susan M

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Feb 1, 2021
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Saw news about this today. This article is from Jan 26th. Could be promising.

Over-the-Counter Nasal Spray Could Be Effective Against COVID-19

Published: Jan 26, 2021 by Alex Keown

https://www.biospace.com/article/mo...al-spray-is-effective-against-covid-19-virus/


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New research suggests an over-the-counter nasal spray is effective at significantly reducing and nearly eliminating SARS-CoV-2, the virus that causes COVID-19 after a single dose.

An in vitro study conducted by scientists from Northwestern University and Utah State University concluded that components found within the Xlear nasal spray, particularly grapefruit seed extract and xylitol, were successful in statistically reducing the amount of SARS-CoV-2.

After a single blast, the researchers saw the nasal spray reduced virus from 4.2 to 1.7 log10 CCID50 per 0.1 mL, a statistically significant reduction of 2.5 log10 CCID50.” News of the study was announced by Xlear and the company said this is only the latest research that reaches a conclusion the over-the-counter spray is effective against the virus that causes COVID-19.

Xlear is currently sold as a nasal irrigant for cleansing and moisturizing the nasal cavities.

Professor Mark Cannon of the Feinberg School of Medicine at Northwestern University said the study breaks ground in two areas. Cannon said using electron microscopy, the researchers saw visual evidence that showed the combination of xylitol and grapefruit seed extract counters the virus. The grapefruit seed extract kills the virus, while the xylitol prevents the virus from attaching to the cell walls, Cannon said in the announcement. The study postulates that xylitol acts as a decoy target for SARS-CoV-2, preventing virus attachment to the core protein on the cell wall, he said.

“In addition to countering SARS-CoV-2, Xlear is likely effective in preventing the spread of future H1N1 viruses, including the emerging SARS-CoV-2 variants, along with other viral epidemics. Given the more transmissible variants we now face, this is critical now,” Cannon said in a statement.

That in vitro evidence will no doubt be used to support a new petition before the World Health Organization. This week, a coalition of health professionals petitioned the World Health Organization to issue Guidance calling on: “all people to use nasal sprays to combat the COVID-19 pandemic.” The petition, which is supported by Xlear, is touting data that shows these nasal sprays are able to block viral adhesion and even kill or deactivate the virus in the nasal passages. The petition calls specifically for WHO Guidance to focus on the use of nasal sprays that contain Xylitol and grapefruit seed extract, which is found in Xlear.

“Nasal sprays are proven safe, inexpensive, non-invasive, easy to use and you can get them off-the-shelf at your local store around the world. There is a growing body of data that sprays, in particular Xlear, can help combat the COVID-19 pandemic. It’s pure commonsense,” Nathan Jones, chief executive officer of Xlear said in a statement.

In December, Xlear filed a Pre-Emergency Use Authorization request with the U.S. Food and Drug Administration in hopes of securing authorization of the spray as a new hygiene tool to help in combat the SARS-CoV-2 virus.

Xlear isn’t the only nasal spray that is showing promise in providing another level of protection against COVID-19, which has infected nearly 100 million people across the globe and led to the deaths more than 2 million people. Researchers from the University of Birmingham in the U.K. developed a nasal spray that can potentially provide protection against COVID-19. The spray uses compounds that are already approved by regulatory authorities in the UK, Europe and the U.S., including carrageenan, along with a gellan polysaccharide.

Another nasal spray that uses a lipopeptide, a cholesterol particle linked to a chain of amino acids, has also shown promise in preclinical testing. As BioSpace previously reported, the lipopeptide matches the stretch of amino acids in the spike protein of SARS-CoV-2 exactly. The lipopeptide attaches itself onto one of the spike’s amino acid chains and prevents viral attachment.
 
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RMT

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Feb 19, 2021
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Israel is testing (clinical trials) a nasal spray with significant promising results for treatment AND preventative.
Makes sense.

I've personally used NASALCORT daily for the past 2 years with great success against allergies, sinus infections and the common cold. And, coincidently haven't been sick. As the name indicates on this OTC product it has enough corticol steroid to legally sell over the counter. It's well worth the money.

Remember the physician in Midland/Odessa, TX, that had treated his COVID patients with steroids used for asthma with 99.9% success rate. Makes sense inhalation is the key to a good response, NOT a jab.

Israeli behind ‘game-changing’ Covid nasal spray says it’s 99.9% effective,
JEWISH NEWS, By ELLIE JACOBS January 13, 2021, 12:52 pm
The SaNOtize Nitric Oxide Nasal Spray (NONS)

"NONS is designed to kill the virus in the upper airways, preventing it from incubating and spreading to the lungs."


SNIPPED:

Lab tests on the SaNOtize treatment at Utah State University’s Antiviral Research Institute confirmed that the company’s Nitric Oxide Releasing Solution inactivated more than 99.9% of SARs-CoV-2, the virus that causes Covid-19, within two minutes.

The SaNOtize treatment is based on nitric oxide, a natural nanomolecule produced by the human body with proven anti-microbial properties shown to have a direct effect on SARS-CoV-2, the virus that causes Covid-19. The treatment can be delivered by nasal spray, throat gargle or nasal lavage.

NONS which Regev describes as “a super simple nasal spray” is unique in that it not only creates a preventative barrier but also kills the virus too.
 
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